Leukaemia Clinical Trials

Ongoing Leukaemia Trials @ NCIS - Patient Recruitment


Protocol Title and Number Patient Selection Criteria Principal Investigator

Pilot Study of Expanded, Activated Haploidentical Natural Killer Cell Infusions for Non-B Lineage Acute Leukaemia and Myelodysplastic Syndrome

 

Patients who have one of the following diagnosis:

  • Acute Myeloid Leukaemia
  • Myelodysplastic Syndromes (RAEB I/II)
  • T-cell Acute Lymphoblastic Leukaemia 
  • Persistent detectable residual disease (no more than 20% blasts in the bone marrow by flow cytometry) despite being treated with standard therapies
  • A suitable donor who is a family member with greater than or equal to 3 of 6 tissue protein match
Dr Koh Liang Piu

Pilot Study of Redirected Haploidentical Natural Killer Cell Infusions for B-Lineage Acute Lymphoblastic Leukaemia

 

  • Patients will B-ALL who have presistent detectable residual disease (no more than 25% blasts in the bone marrow by flow cytometry) despite being treated with standard therapies
  • Patients must have a suitable donor who is a family memeber with a greater than or equal to 3 of 6 tissue protein match
Dr Tan Poh Lin

A Multi-centre Phase III Randomised, Open-label Study of Bosutinib versus Imatinib in Adult Patients with Newly Diagnosed Chronic Phase Chronic Myelogenous Leukaemia

Patients within 6 months of diagnosis who have not received any treatment for Chronic Myelogenous Leukaemia before Dr Koh Liang Piu

Single Institution, Phase I clinical trial on the safety and tolerability of a novel combination anti-Leukaemic therapy with Flt3 inhibitor and HDAC inhibitor in Acute Myeloid Leukaemia patients who are ineligible for intensive chemotherapy and in those who have relapsed and refractory disease (*Expected to start recruitment in May 2015) 

Patients must have had been treated with standard treatment for Acute Myeloid Leukaemia but are not responding to the treatment OR are unfit for further intensive treatment Dr Ng Chin Hin

Updated as of 6 April 2015


Contact Information

Are you interested to participate in a clinical trial?

 

To find out if you are eligible for a particular clinical trial, talk to your doctor at our Cancer Centre today.


For more information please contact:

 

Ms Vilianty
Clinical Research Administrator
DID : +65 6772 4619
Email: vilianty@nuhs.edu.sg 

 

Miss Joan Phee
Research Administrator
DID : +65 6772 2404
Email: joan_phee@nuhs.edu.sg