Dr Brendan Pang

Consultant, Department of Pathology, NUH Instructor, Clinician-Educator Tract, Department of Pathology, Yong Loo Lin School of Medicine, NUS Laboratory Director and Co-Director, Diagnostic Molecular Oncology Centre, Department of Pathology, NUHS

Education and Fellowships

MBBS (NUS), FRCPath, Fellowship in Molecular Anatomic Pathology Laboratory (University of Pittsburgh Medical Center)

 

Specialty Interests

• Cyto-pathology
• Diagnostic molecular pathology

• Cancer biomarker discovery and validation
  

 

Awards and Honours

• National University Cancer Institute, Singapore (NCIS) Centre Grant - Junior Investigator Protected Time Grant FY 2010 - 2011

 

Selected Publications (out of 12)

1. Yan B, Yau EX, Bte Omar SS, Ong CW, Pang B, Yeoh KG, Salto-Tellez M A study of HER2 gene amplification and protein expression in gastric cancer. J Clin Pathol. 2010 Sep;63(9):839-42.
2. Yan B, Yau EX, Choo SN, Ong CW, Yong KJ, Pang B, Salto-Tellez M. Dual-colour HER2/Chromosome 17 chromogenic in situ hybridisation assay enables accurate assessment of HER2 genomic status in gastric cancer and has potential utility in HER2 testing of biopsy samples J Clin Pathol. 2011 Jul 14 [Epub ahead of print] PMID: 21757431
3. Petersson F, Pang B, Thamboo TP, Putti TC. Mucinous cystadenocarcinoma of the breast with amplification of the HER2-gene confirmed by FISH: The first case reported. Hum Pathol. 2010 Jun;41(6):910-3.
4. Pang NK, Nga ME, Chin SY, Ismail TM, Lim GL, Soong R, Salto-Tellez M. KRAS and BRAF mutation analysis can be reliably performed on aspirated cytological specimens of metastatic colorectal carcinoma. Cytopathology. 2010 Oct 4. doi: 10.1111/j.1365-2303.2010.00812.x. [Epub ahead of print]
5. Pang NK, Chin SY, Nga ME, Chang AR, Ismail TM, Omar SS, Charlton A, Salto-Tellez M. Comparative validation of c-kit exon 11 mutation analysis on cytology samples and corresponding surgical resections of gastrointestinal stromal tumours. Cytopathology. 2009 Oct;20(5):297-303. Epub 2009 Jan 21.
6. Kothandaraman N, Bajic VB, Brendan PN, Huak CY, Keow PB, Razvi K, Salto-Tellez M, Choolani M. E2F5 status significantly improves malignancy diagnosis of epithelial ovarian cancer. BMC Cancer. 2010 Feb 24;10:64.
7. Shah N, Pang B, Yeoh KG, Thorn S, Chen CS, Lilly MB, Salto-Tellez M. Potential roles for the PIM1 kinase in human cancer - a molecular and therapeutic appraisal. Eur J Cancer. 2008 Oct;44(15):2144-51
8. Soon WW, Miller LD, Black MA, Dalmasso C, Chan XB, Pang B, Ong CW, Salto-Tellez M, Desai KV, Liu ET. Combined genomic and phenotype screening reveals secretory factor SPINK1 as an invasion and survival factor associated with patient prognosis in breast cancer. EMBO Mol Med 2011 Aug;3(8):451-64.
9. Petersson F, Pang B, Loke D, Hao L, Yan B. Biphasic Low-Grade Nasopharyngeal Papillary Adenocarcinoma with a Prominent Spindle Cell Component: Report of a Case Localized to the Posterior Nasal Septum. Head Neck Pathol 2011.