Cancer Singapore | National University Cancer Institute, Singapore (NCIS) > Patient and Visitors > Our Services > Cancer Risk Assessment and Genetics Clinic

Cancer Risk Assessment and Genetics Clinic


Cancer genetics service has been offered by the NCIS since 2001. The cancer genetics service provides genetic counselling to individuals with a personal and/or family history of cancer. Most cancers occur by chance. However, a small percentage of cancers are caused by an inherited gene mutation, or are hereditary. Identifying a genetic predisposition to cancer allows patients and their families to personalise cancer screening guidelines, medical care and treatment options. 



Who should go for genetic evaluation and counselling?

 

Genetic evaluation and counselling will be beneficial to you if you have a personal or family history of the following:


  • Young onset cancer (e.g. breast cancer before age 40 or colon cancer before age 50)
  • Multiple family members affected by the same type of cancer or related cancers (e.g. breast and ovarian, colon and uterine)
  • Multiple primary cancers diagnosed in one individual
  • Ashkenazi (Eastern Europe) Jewish ancestry and breast or ovarian cancer
  • Known genetic mutation in the family
  • Rare tumours (e.g. male breast cancer, paraganglioma, medullary thyroid cancer)
  • Presence of other clinical features associated with an inherited cancer syndrome (e.g. multiple colonic polyps)


The genetic counselling process

 

Patients referred to the cancer genetics service are evaluated and counselled individually or with their family members. During each new consultation, the patient's cancer and family histories are evaluated and an assessment is done.


Patients suspected of having a genetic predisposition of a particular genetic syndrome are counselled on the following:

 

  • Genetic education and counselling on suspected genetic syndrome  
  • Discussion of lifetime risks of cancers associated with suspected syndrome
  • Potential benefits and risks of genetic testing
  • Personalised screening recommendations for patient and family members
  • Recommendations on preventive options for cancer prevention  
  • Options for research participation

 

If genetic testing is indicated, blood can usually be drawn on the same day following the counselling session. 

 

Our Cancer Genetics Team

 

Our cancer genetics team is committed to providing comprehensive clinical genetic services, education and support to patients and their family members.


The cancer genetics service is directed by Dr Lee Soo Chin, a Medical Oncologist trained in cancer genetics at the John Hopkins University School of Medicine, USA, and was credentialed in ‘Familial cancer risk assessment and management’ by the Institute for Clinical Evaluation in the USA.  



Adjunct Associate Professor Lee Soo Chin

 

Associate Director (Research) & Senior Consultant

Department of Haematology-Oncology 

National University Cancer Institute, Singapore (NCIS)


Adjunct Research Associate Professor

Cancer Science Institute of Singapore, NUS



Click here to view her full profile.

 

 

 

Ms Ong Pei Yi


Cancer Genetics Counselor

B Sc (Hons)



 




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