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Dr Derrick Lian

Designations:
  • Senior Consultant, Department of Pathology, National University Hospital
  • Assistant Professor, Yong Loo Lin School of Medicine, National University of Singapore
Qualifications:
MBBS (Singapore), FRCPath (UK), MHPE
Specialties:
Pathology
Special Interests:
Paediatric tumours​

Biosketch

Dr Derrick Lian completed his basic medical education in the National University of Singapore. Following his housemanship, Dr Lian trained in Histopathology and was accepted as a fellow of the Royal College of Pathologists (UK). He then subspecialised in Paediatric Pathology, having trained and worked in KK Women’s and Children’s Hospital, before joining the National University Hospital.

Dr Lian is also active in the field of medical education, and is involved in both undergraduate as well as postgraduate teaching. He has a Masters in Health Professions Education with distinction, and is especially interested in interprofessional education to enhance patient care.

Awards

NUH Teaching Excellence Award 2016​

Journals & Publications

​1. Chng SY, Van Bever HP, Lian D, Lee SX, Xu XN, Wang XS, Goh DYT.  Relationship between exhaled nitric oxide and atopy in Asian young adults.  Respirology. 2005; 10(1): 40-5.

2. Lian D, Cheah E, Tan PH, Thng CH , Tan SM. Phyllodes tumour with intraductal growth: a rare cause of nipple discharge. Histopathology. 2007; 50(5): 666-9.

3. Lian DWQ, Chuah KL, Cheng MHW, Yap YM. Malignant perivascular epithelioid cell tumour of the fibula: a report and a short review of bone perivascular epithelioid cell tumour.  Journal of Clinical Pathology. 2008; 61: 1127-1129.

4. Lian DWQ, Chau YP, Lee LK, Teo C, Yap WM, Chuah KL. Ocular mantle cell lymphoma with aberrant CD10 expression: a potential diagnostic pitfall. Pathology. 2009; 41(7): 704-6.

5. Lian DW, Lee HY, Tan KK, Sitoh YY, Yap WM, Chuah KL. Proximal type epithelioid sarcoma arising in the base of skull: a diagnostic challenge. Journal of Clinical Pathology. 2010; 63(5): 472-4.

6. Lee HY, Ng I, Quan Lian DW, Yap WM, Chuah KL. Cytological features of the native pineal gland in intraoperative squash preparations. Diagnostic Cytopathology. 2011; 39(3): 196-9.

7. Petersson F, Lian D, Chau YP, Yan B. Mammary analogue secretory carcinoma: The first submandibular case reported including findings on fine needle aspiration cytology. Head and Neck Pathology. 2012; 6(1): 135-9.

8. Lian DW, Lam JC, Aung AC, Li FX, Chang KT. Intestinal atresia occurring in association with placental fetal thrombotic vasculopathy: a case report with literature review. Pediatric and Developmental Pathology. 2013; 16(1): 28-31.

9. Lian DWQ, Li FX, Ong CCP, Kuick CH, Chang KTE. Pseudomembranous trigonitis in a male with Klinefelter syndrome: a case report and evidence of a hormonal etiology. International Journal of Clinical and Experimental Pathology 2014;7(6): 3375-3379.

10. Loh TJZ, Lian DWQ, Iyer P, Lam JCM, Kuick CH, Aung ACL, Chang KTE. Congenital GATA1-mutated myeloproliferative disorder in trisomy 21 complicated by placental fetal thrombotic vasculopathy. Human Pathology 2014; 45: 2364–2367.

11. Yan B, Kuick CH, Lim M, Venkataraman K, Tennakoon C, Loh E, Lian D, Leong MY, Lakshmanan M, Tergaonkar V, Sung WK, Soh SY, Chang KTE. Platform comparison for evaluation of ALK protein immunohistochemical expression, genomic copy number and hotspot mutation status in neuroblastomas. PLoS One. 2014 Sep 4;9(9):e106575.

12. Chiou FK, Lian DWQ. Primary intestinal lymphangiectasia of the terminal ileum. . The Journal of Gastroenterology and Hepatology. 2015; 30: 1335.

13. Aw SJ, Wang S, Loh AH, Kuick CH, Lian DW, Yong MH, Ling S, Peh GL, Soh SY, Loh AH, Tan PH, Chang KT. Novel karyotypes and cyclin D1 immunoreactivity in clear cell sarcoma of the kidney.  Pediatric and Developmental Pathology. 2015; 18(4): 297-304.

14. Seow EI, Loh AHP, Lian DWQ, Nah SA.Thyroglossal duct cyst carcinoma: diagnostic and management considerations in a 15-year-old with a large submental mass. BMJ Case Reports. 2015: bcr2015210923.

15. Varanasi VRK, Leong MY, Tan AM, Lian WQD, Teo ELHJ. Langerhans cell histiocytosis: another cause of a fluid–fluid level within an appendicular bony lesion. BJR Case Reports. 2016; 2: 20150408.

16. Qi M, Chang ETK, Lian DWQ, Khoo CK, Tan KH. Placental massive perivillous fibrinoid deposition is associated with adverse pregnancy outcomes: a clinicopathological study of 12 cases. Case Reports in Perinatal Medicine. 2016; 5(1): 35-39.

17. Chen Y, Chang KT, Lian DW, Lu H, Roy S, Laksmi NK, Low Y, Krishnaswamy G, Pierro A, Ong CC.  The role of ischemia in necrotizing enterocolitis. Journal of Pediatric Surgery. 2016; 51(8): 1255-1261.

18. JH Teo, MY Chan, DWQ Lian, R Bhattacharyya, P Iyer.  Inflammatory myofibroblastic tumors: A tale of three stories.  Pediatric Hematology Oncology Journal. 2016; 1(2): S28.

19. Chua FH, Thien A, Ng LP, Seow WT, Low DC, Chang KT, Lian DW, Loh E, Low SY. Post-operative diffusion weighted imaging as a predictor of posterior fossa syndrome permanence in paediatric medulloblastoma. Child's Nervous System. 2017 Feb 11:1-9.

20. Chua FH, Low DC, Lian DW, Tew SW, Low SY. Anomalous intracranial germinoma with unilateral cerebral peduncle swelling.  Child's Nervous System. 2017 Mar 10:1-3.

21. Chua FH, Low DC, Lian DW, Ng LP, Chang KT, Loh E, Seow WT, Low SY. Medulloblastoma with tri-vergent melanocytic, myogenic and cartiligious elements. Journal of Clinical Neuroscience. 2017; 41: 100-103.

22. Low SY, Lian DW, Tang PH, Loh E, Seow WT, Low DC. Concurrent paediatric medulloblastoma and Chiari I malformation with syringomyelia. Child's Nervous System. 2017; 33(6): 881-883.

23. Hue SS, Iyer P, Toh LH, Jain S, Tan EE, Sittampalam K, Lian DW, Chang KT. Primary bone anaplastic large cell lymphoma masquerading as Ewing sarcoma: diagnosis by anchored multiplex PCR. Journal of Pediatric Hematology/Oncology. 2017;40(2):e103-7.

24. Lee EY, Lian WQ, Iyer P, Bhattacharyya R. An unusual cause of fever and rash in a child with severe aplastic anemia.  Journal of Pediatric Hematology/Oncology. 2017; 40(2): 156-8.

25.  Wong MK, Ng CCY, Kuick CH, Aw SJ, Rajasegaran V, Lim JQ, Jain S, Loh E, Yin MZ, Ma J, Zhang Z, Iyer P, Loh AHP, Lian DWQ, Wang S, Goh SGH, Lim TH, Lim AST, Ng T, Goytain A, Loh AHL, Tan PH, The BT, Chan KTE. Clear cell sarcoma of kidney is characterized by BCOR gene abnormalities including exon 15 internal tandem duplications and BCOR-CCNB3 gene fusion. Histopathology. 2018; 72(2);320-329.

26. Chua JY, Ling JM, Lian DW, Chan MY, Low DC, Low SY. Atlanto-axial subluxation with torticollis secondary to Langerhans cell histocytosis. Interdisciplinary Neurosurgery. 2017; 10: 101-103.

27. Tay TK, Guan P, Loke BN, Md Nasir ND, Rajasegaran V, Thike AA, Lian D, Chang KT, Teh BT, Ng CC, Tan PH. Molecular insights into paediatric breast fibroepithelial tumours. Histopathology. 2018; 73(5): 809-818.

28. Koh NW, Seow WY, Lee YT, Lam JC, Lian DW. Pericytoma with t (7; 12): The first ovarian case reported and a review of the literature.  International Journal of Gynecological Pathology: Official Journal of the International Society of Gynecological Pathologists. 2018 Aug.

29. Loke BN, Wong MK, Tawng KD, Kuick CH, Jain S, Lian D, Wagner E, Zou Y, Ganesan V, Sim SW, Lee YT. Clinical, pathological and loss of heterozygosity differences in Wilms tumors between Asian and non-Asian children. International Journal of Cancer. 2019 Mar 15;144(6):1234-42.

30. Low SY, Kuick CH, Seow WY, Sulaiman NB, Chen H, Lian DW, Chang KT, Tan EE, Soh SY, Tan GI, Ng LP. Primary paediatric epidural sarcomas: molecular exploration of three cases. BMC Cancer. 2019 Dec;19(1):182.

Professional Memberships

  • Royal College of Pathologists, UK
  • Singapore Medical Association