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Clinical and Treatment Outcomes

2025/11/07
Breast Cancer

The following table shows the survival information of patients diagnosed with breast cancer at NCIS in 2018. The 5-year cancer-specific survival rate reflects the percentage of these patients who remain alive at the 5th year, according to their diagnosed breast cancer stage. Breast cancer demonstrates excellent survival outcomes across early stages at NCIS, with 100% survival for stage 0 disease and 98.3% for stage I. Stage II maintains strong survival at 94.9%, whilst stage III shows 80.5% survival. Advanced stage IV disease presents more challenging outcomes with 44.7% 5-year survival, reflecting the impact of metastatic disease on prognosis.

 

Colorectal Cancer

The following table shows the survival information of patients diagnosed with breast cancer at NCIS in 2018. The 5-year cancer-specific survival rate reflects the percentage of these patients who remain alive at the 5th year, according to their diagnosed breast cancer stage. Breast cancer demonstrates excellent survival outcomes across early stages at NCIS, with 100% survival for stage 0 disease and 98.3% for stage I. Stage II maintains strong survival at 94.9%, whilst stage III shows 80.5% survival. Advanced stage IV disease presents more challenging outcomes with 44.7% 5-year survival, reflecting the impact of metastatic disease on prognosis.

Diffuse Large B Cell Lymphoma Cancer

The following table shows the survival information of patients diagnosed with Diffuse Large B Cell Lymphoma (DLBCL) at NCIS in 2018. The 5-year cancer-specific survival rate reflects the percentage of these patients who remain alive at the 5th year, according to their diagnosed Diffuse Large B Cell Lymphoma (DLBCL) stage. DLBCL cancer demonstrates exceptional survival outcomes across localised and regional stages for patients treated at NCIS, with 100% survival for stage I, 71.4% for stage II, and 40 % for stage III. Even advanced stage IV disease maintains relatively favourable survival at 59.3 %, reflecting effectiveness of available treatments.

Haematopoietic Stem Cell Transplant / Bone Marrow Transplant Programme

NCIS success rate for the Haematopoietic Stem Cell Transplant / Bone Marrow Transplant Programme is comparable to the international registry data at the Centre for International Blood & Marrow Transplant Research (CIBMTR) and the European Group for Blood and Marrow Transplant (EBMT).

Type of transplantDiseasesNCIS Survival OutcomeInternational Survival OutcomeReferences
Matched Sibling Donor (MSD) TransplantAcute Leukaemia~50% at 5 years (2005 - 2016)~50% at 5 years (2001 - 2018), CIBMTRCheryl Lim, Koh LP et al. EBMT 2017
Matched Unrelated (Volunteer) Donor (MUD) TransplantAcute Leukaemia~50% at 5 years (2005 - 2016)~50% at 5 years (2001 - 2018), CIBMTRCheryl Lim, Koh LP et al. EBMT 2017
Unrelated Umbilical Cord Blood (UCB) TransplantHaematological Cancers~50% at 3 years (2007 - 2019)~40% at 5 years (2005 - 2016), EBMT

Ian Wu, Koh LP et al. ASH 2020.

Ruggeri A, et al. Leukemia 2015.

Sequential Transplant Using Matched Related/Unrelated DonorHaematological Cancers~60% at 3 years (2006 - 2020)~55% at 3 years (2007 - 2019) (EBMT)

Chong LL, Koh LP, et al. ASH 2020.

Malard F, et al. BBMT 2017

Haploidentical (mismatched related) donor transplant using Haplo-2017 PlatformHaematological Cancers~60% at 2 year (2012 - 2019)60% at 2 year (2012-2019), BMT-CTN 1101 study

Koh LP et al. BMT 2025.

Koh LP et al. ASH 2022.

Fuchs EJ et al. Blood 2021

References:

  • Centre for International Blood & Marrow Transplant Research, www.cibmtr.org
  • European Group for Blood and Marrow Transplantation, www.ebmt.org

(Information is correct as at July 2022)

Lung Cancer

The following table shows the survival information of patients diagnosed with lung cancer at NCIS in 2018. The 5-year cancer-specific survival rate reflects the percentage of these patients who remain alive at the 5th year, according to their diagnosed lung cancer stage. Lung cancer demonstrates excellent survival for for patients treated at NCIS with early-stage disease with 97.2% survival for stage I. However, survival decreases substantially with advancing stage, showing 77.4% for stage II, 39.9% for stage III, and 16.5% for stage IV. These outcomes underscore the critical importance of early detection in lung cancer management.

Prostate Cancer

The following table shows the survival information of patients diagnosed with prostate cancer at NCIS in 2018. The 5-year cancer-specific survival rate reflects the percentage of these patients who remain alive at the 5th year, according to their diagnosed prostate cancer stage. Prostate cancer demonstrates exceptional survival outcomes across localised and regional stages for patients treated at NCIS, with 100% survival for stage I, 97.4% for stage II, and 95.7% for stage III. Even advanced stage IV disease maintains relatively favourable survival at 43.8 %, reflecting effectiveness of available treatments.

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